Setback Strategy Guide

Third option:  Play Wrong Time and Place.  Use the tokens to redirect the damage from Looking Up to a target and use Looking Up to replenish said tokens.  A bit riskier with High Risk Behavior in play (and more expensive!) but it will also drop your tokens lower and give your allies some defense.  A risky option, but well worth it if successful.

 

Edit: I also agree with Karmic Retribution being his weakest offensive card.  It is too expensive for what it does.  If it removed tokens after the hit, it would be amazing as it would take advantage of High Risk Behavior.  As it is, it's really an "in case of emergency, break tokens" button.