Hmmm ... sorry to be so wishy-washy, but I'm no longer convinced that I agree and might re-pedal, if you will.
Hopefully, my brain is just working poorly and someone can point out the error of my ways.
In regards The Informant causing a villain card to be played before any card played is resolved, I can think of two different reasons this might be the case: 1) A card being played is seperable and comes before a card entering play and cards being played don't have text until the card enters play, and 2) The Informant was in play before whatever card is played/enters play, so it gets to trigger a villain card before whatever the entering card does anything.
So far, I don't think it matters what the reasoning is.
Consider, however, Take Down, which stops villain cards from being played. It is not a triggered action, per se, but a static 'rule', if you will. If we use the second reasoning above (The Informant was in play before whatever card is entering play), then the reason that The Informant gets triggered before whatever is being played might destroy The Informant is that, since no two actions are ever truly simultaneous, card order means that The Informant gets to trigger before, say, Back Fist Strike can do damage that would destroy the The Informant.
Take Down, however, does not do an action. It changes the rules. So there's no order of actions that needs to resolve. The card is played, causing it to enter play and change the rules. The Informant than triggers and is not allowed to play a villain card.
Does this cause any problems with the PEF ruling? I don't think so. PEF is in play before another distortion is played, so when it comes down to determining which goes first of PEF doing something versus the new distortion causing PEF to go away, since PEF was in play first, it goes first.