Yeah, I think it’s safe to say that the Inversiverse is the biggest alternate universe, Ivana’s the biggest character within it, and that she’s probably the biggest alternate reality character who hasn’t had any major interactions with Universe 1. (So, she’s right after Iron Legacy, Miss Information, the Visionary, Dark Visionary, and KNYFE.)
The Inversiverse also has genderbent Fright Train.