The only time I did him on Advanced (in Rook City) involved: Scholar, TLT, Greatest Legacy, Tempest, Argent Adept
Game went our way but it still had close calls. I recycled Proverbs and Axioms and played it many many times for team healing, we never got next evolution so we had to rely on damage reduction with scholar pretty much taking everything striking the highest HP and Legacy taking care of Chairman retaliations.
It's not a guarantee or anything, but:
Scholar (Flesh to Iron, and, uhm… really, that's about it)
Legacy (Next Evolution, Lead from the Front, maybe Legacy Ring)
Visionary (Brain Burn)
Tempest (Lightning Storm)
Scholar tanks against the Operative with FtI and his innate power until Legacy gets NE/LftF out, and then everyone is immune to melee and can kill the bad guys with impunity. Tempest kills everyone. Visionary shuffles the trash into villain deck as early as possible so that the Underbosses can stand around confused and if necessary keeps any Jailbreaks from being played.
With this team, it's still hard to beat the Chairman advanced, since you'll inevitably pull the Contract as the first underboss before you're set up and either die to the Hitmen over the next couple of turns or kill the Contract, flip the Chairman, and die because you're not set up. However, if you the Contract comes out late, Scholar can just tank the Operative while you keep destroying minions. Once Legacy is set up, it's all over.
Ronway… 
Play nice. 
Also, pillars of Hercules combined with the informant in the first round. In a 5 hero game he reshuffles in the first round which makes him pretty easy with a bit of AoE
Me and my brother took The Chairman apart with Haka, Parse, Chrono Ranger and The Argent Adept.
Counterpoint Bulwark + Té Moko pretty much negated the Operative's counterstrike ability, and Buffer Overflow prevented Prison Break from ruining our day. Critical Multiplier let Parse stack up big damage buffs to make it easy to take out The Chairman in very few hits, and we were playing in the Mobile Defence Platform, which Haka was able to negate with Endruing Intercession.
Hmmm… Haven't heard of that game, I will look into it. Does it play anything like Sentinels of the Multiverse?
How to wipe Chairman:
Legacy, Parse, Unity, Omnitron-X
Flip Chairman (kill the first underboss)
+2 from Legacy, Irreducible damage and +1 to Operative from Parse, Unity uses Hasty Augmentation on Omnitron-X who uses Defensive blast.
At +4 all targets take 20 irreducible damage, 24 to Operative. Then Omni does it again for 12 to everyone, 16 to operative. Thats a second round wipe of the organization, requires:
1 card from Legs, 3 from Parse (need big luck there), 1 from Unity and three from Omni, but his can be pulled.
Version 2:
Mr. Fixer, Parse/Legacy/Visionary/Adept, DW Expat, Tachyon/Wraith/Scholar
The idea is get Expat to +2 damage with Hairtrigger, which removes Hitman from being a threat and pretty much seals the game for the heroes. Fixer is there to tank Operative with Hoist chain or Mantis, then someone who can give the +1 damage to Expat, and someone who can stop Chairman's retaliation damage for a few rounds.
Version 3:
Haka, Mr. Fixer then either Visionary and Omnitron-X or Tempest and Scholar. This version you just get Ground Pound and cycle the heck out of it, with grease gun to fill gaps, or work just as well witht he second team.
Version 4: Legacy with two powers, two next Evolutions and lead from the front, be immune to melee and Projectile. Laugh.
That's four ways to completely shut down and crush the Organization.
I've beat Chairman over a dozen times, and only two used any of these.
My favorite is AZ and Visionary, TTE on Chairman, then just let AZ kill him, while Chairman's retaliation either heals AZ or causes a lot more damage to Chairman. A second TTE on Operative makes the game a cake walk.
Unity, Wraith, Nightmist: Stealthbot, Smoke Bombs, and Mistform (and highest Hp) = no damage until something gets blown up.
I'm more of a 3 hero team kind of guy. One of the ones;
Legacy, Tempest, and Expatriette.
Legacy with Fortitude, Lead From the Front, and Inspiring Presence.
Tempest with Gene-Bound Shackles and Electrical Storm. Grevious Hailstorm would be good as well, but the extre point isn't really needed.
Expatriette with Hair Trigger Reflexes and Assault Rifle.
It works on both advanced and non-advanced, only difference being is on advanced Legacy will take a bit of damage from Chairman's damage, but if every hero is setup like this, Chairman and Operative will be taking 11 damage a round, not including any one-shots or ammo getting played. And really, any gun would be fine for Expatriette.
That's only on Advanced, and I've only dared play advanced Chairman once, it's pretty suicidal and I haven't dared try again.
Irreducible damage and +1 to Operative from Parse
Er, how are you doing both those things on just one turn?
Unity uses Hasty Augmentation on Omnitron-X who uses Defensive blast.At +4 all targets take 20 irreducible damage, 24 to Operative. Then Omni does it again for 12 to everyone, 16 to operative. Thats a second round wipe of the organization
Omni needs two cards in play before his turn for that to work. You'd have to get absurdly lucky with Timeshift. I'm okay with a plan that assumes ideal luck drawing cards, since you only need like two cards to be among the four in your opening hand, plus the one you draw after your first turn. But ideal luck with a single card flip is too much to ask for to make any kind of strategy around.
That's four ways to completely shut down and crush the Organization.
At least two of which rely on you having certain specific heroes. The ones that seem mandatory so far are those that can mitigate damage - Legacy, Scholar, Wraith, maybe Tachyon though I don't think you mentioned her, Fixer and Expat can do a little of it, Haka could do it if you could manage to get him enough extra card draw and paired him with Argent or Tempest (Scholar only has two DDAs, so cycling Ground Pound forever with that is a long shot). Can it be done without these heroes? Can it be done by these heroes without ideal luck? Do you have better than a 20% or so chance of pulling it off? It's not strictly impossible, but if it requires this much Cloudcuckooland to succeed, it's sufficiently close to deserve the name.
Did you forget the point? If so, there was a statement that I made, saying every villain can be made easy with the right team and the right cards. That was followed by you asking what these teams and cards were for The Chairman. You have received an answer, yet you are not satisfied with it. Perhaps before asking questions, you ask yourself, do I really want to get an answer or am I just setting it up so I can complain about the statistics of it happening?
Play some games. A lot of games.
You know what's awesome?
That we have a whole project devoted to working out what heroes win what percentage of times, we can even narrow it down to heroes verses a particular villain. Why, with a click of a button I can see the very results that you want. If you poke around a bit further you can see the raw data so that you can see who else was on the team when a hero won against that villain, that way you don't need to rely on Ronway's suggestions.
With two turns to defensive blast that is two play phases before you defensive blast, so no luck on timeshift required.
Parse requires snap decision to pull it off, or an our of turn card play. The time we did that Omnitron's first turn he timeshifted Parse, and got snap decision, so it was awesome.
Those examples are completely dominating Chairman to the point that he poses no legit threat to the heroes.
I've beaten him with all sorts of teams. He doesn't give me as much trouble as dreamer.
I think he's better on advanced, his second side is meaner, but he does far less to you before you can kill him. If you are at half health when he flips you are toast. Advanced solves that for you.
But statistics are evil! And wrong! Evil and wrong!
And 73.4% of them are totally made up!
I thought it looked like you were saying O-X needed to Defensive Blast once off of Unity's Hasty Augmentation, then once more on his own turn. O-X would need to play both Defensive Blast and a Plating card before that could happen, so he must have had two turns. If Unity's turn is before his, this can't happen without the luck I alluded to; if her turn is after his, then your example was misleadingly worded.
Those examples are completely dominating Chairman to the point that he poses no legit threat to the heroes.
I would have said that was impossible. What if he Prison Breaks? No matter how good your setup is, other than Next Evo/Lead from the Front, I don't see how he can be completely neutralized. And even then, Rook City is Mine might put out Environment threats which Lead from the Front doesn't stop.
If you are at half health when he flips you are toast. Advanced solves that for you.
Well I can see that making sense, but usually I am at half health when he flips, even if I do manage to squeak out a narrow win. I suppose I can try more Advanced games, though frankly I'm not wanting to deal with the whole "shuffling the Chairman" issue.
That information does not go into enough detail to be particularly useful. It doesn't list what cards a hero drew during games when they won against the Chairman, or what order they were played, or any of that. And if I went to the statistics and saw that, say, Parse had a 76% win rate against Chairman and I went and played three games against Chairman with her and lost more than one of them, I'd feel tremendously stupid for ever thinking that the statistics were telling me anything. So I just proactively don't listen to them in the first place. More detailed information is more useful to me, but ultimately Ronway's not wrong that I shifted the goalposts a bit; the bottom line is, Chairman is really hard, even with a team specifically built to beat him, you still need above-average luck to get a setup which can even prevent you from losing, let alone enable you to win. And if you want to play any old hero instead of just certain heroes, or pursue strategies other than the most optimal ones, you'll do even less well. The Chairman is NOT someone you play when your objective is to have fun, unless your definition of fun is tackling a nigh-impossible challenge and MAYBE succeeding, if you make only optimal choices AND have better-than-average luck. That's really all I was getting at.
You are perhaps confusing me with Envisioner. Natural mistake, he and I being such good friends and all. But I joined this forum after he got himself banned, and I don't plan on following in his footsteps to such an extent. I'm here to carry forward the good works he created; while we agree on a lot of issues, I'd like to think I've learned more tact and prudence than he could ever quite manage.
I enjoy fighting the chairman and I’ve never put together a team to beat him. I also have beaten him as often as I’ve lost. When you pull the win it feels great
We seem to do fine against the Chairman on G+ with our random heroes. *shrugs* I don't know that we employ any particular strategy or anything...
Yeah mostly we pull a Ronway and play the best cards we have at that time
Edit: for example giving Tempest 4 additional uses of localized hurricanes. Makes the operative go down fast