Some heroes can straight up solo ko villains (those lacking ongoing/event hate) once they get optimal set up. Nightmist and Scholar do this with ease, and so can A/z, but that set up is way way more cards. Anyone else? And if so, how?
Assuming optimal setup, Unity definitely can gib most villains (though she has a long set up).
We had KNYFE completely wreck a villain, though that required very specific circumstances.
Given enough cards in hand, Haka can one-shot pretty much anything.
When he can one shot Akash'Bhuta, like Setback, then we can talk.
But he can! Not with one Haka of Battle, but you can draw your entire deck, discard it HoB, reshuffle and draw it again, discard it to another HoB, and repeat until he has a +999999 to damage.
Admittedly, doing so requires a lot of setup but it is technically possible.
This, I got to hear. How can Setback one-shot Akash'Bhuta?
Just get 200 unlucky tokens and play Cause and Effect.
Or get 588 unlucky tokens, play High Risk Behavior, and use Looking Up.
Both of these are pretty easy to do.
Or get to 120 tokens, 2 High Risks, and a Cause and Effect.
2 High Risks? At the same time!!? Do you have any idea how difficult it is to do that?
On a scale from one to ten, I say blue.
Not that hard. I do it all the time. It's great for racking up damage. I used that to one-shot Proletariat, once.
Shouldn't Parse be able to ruin Gloomweaver's day by throwing all his relics in the trash with just Extrasensory Awareness?
With enough setup time, Parse can also hit for staggering amounts of damage by way of multiple Critical Multipliers and repeated discard effects (Recompile, Gauge, Snap Decision, Segmentation Fault).
Super Scientific Tachyon could also toss all of Gloomy's relics for him, but it'd take a lot more luck for her to pull it off.
SST with a mild bit of luck, Tempest or Argent (to get back Barrage) should work to take out most of the lower point guys too, but I didnt really mean just one Alpha strike. I meant what the above post has - combos for a character where someone can just win a slugfest/War of Attrition vs. Many villains.
Iron Legacy. He often takes out 3-5 villains in a fight.