After some playtesting with the new Void Guard, I've found that Dr. Medico's Malpractice variant is much worse than his basic form/power...
UNLESS you play the right team. With the right team, Malpractice Dr. Medico will absolutely cream the entire villain/environment team, every turn. The trick is to maximize the number of hero targets, and the number of 'heal all hero targets' effects.
Here's the team I've had the most success with:
Legacy (original)
Captain Cosmic (Requittal)
Dr. Medico (Malpractice)
Tempest (Any, but in this team I like his Freedom Six/Sacrifice variant)
Sentinels (Either, but in this team I prefer Adamant)
...
The trick is to get cards into play that heal all targets. Some examples are Legacy's Motivational Charge, Dr Medico's Healing Pulse, Tempest's Cleansing Downpour, and Sentinel's Hippocratic Oath. There are also many Dr. Medico and Sentinels one shots that heal all hero targets as well.
With Captain Cosmic (Requittal) you should be able to get a large number of hero targets into play in just a few turns. Just be sure to put all 'energy bracers' drawn on him, so his own constructs don't hurt him too badly. The Sentinels on their own add 3 more hero targets, and I find that more reliable than using Unity, who usually only has 1-2 machines in play at a time.
Combined, a single use of a 'heal all players' effect can easily cause Dr. Medico's malpractice to go off 8-12 times. Combined with damage/healing boosting effects from Legacy and Dr. Medico himself, each hit and potentially do 3-5 damage. For added fun, have Captain Cosmic drop Autonomous Blade on Dr. Medico, so each hero turn where 'healing' is done, Dr. Medico gets a bonus 2-5 damage attack.
The only catch with this plan is if a target is at full health, then they don't heal, and Dr. Medico's power doesn't go off for them. If at all possible, try to have every target below maximum health, to maximize the number of hits Dr. Medico inflicts each turn.
Side note: it may seem like I'm only including Tempest for cleansing downpour, but it's also because he can reliably deal with enemy ongoing and environment cards, which is otherwise missing from this team. There are other hero choices, obviously (Tachyon, for starters), but I feel Tempest is the best mix of healing, damage, utility, drawing, and anti-ongoing/environment effects.
Have fun!