What is the consensus on when the game actually ends upon the destruction of the villain? For example, will hit-backs like Backlash Field or the Chairman's ability activate when the villain is reduced to 0 or fewer HP (assuming all other conditions for victory have been fulfilled)?
According to the Handelabra/Christopher fireside chat,
However, in my experiments with the digital version of Sentinels, this rule doesn't apply to villains: both Ambuscade (with Reactive Plating) and Baron Blade (with Backlash Field) still get to strike back after being reduced to 0 or fewer HP. This makes it possible for all the characters, villain and hero, to be incapacitated/destroyed (which results in a villain victory, apparently).
At what point do you check for victory? And why do only villains seem to get a pass on striking back from the grave?
If you're unsure you can always post feedback about the issue. I try to include screenshots if possible. The Handelabra is pretty responsive and even send a follow up email once a build is released with the fix in it.
It's not those cards alone - I also had a situation where Fanatic got incapped partway through using Exorcism: she dealt 1 melee damage to Blade, got incapacitated by a Backlash Field in response, but was then still able to deal the 1 radiant for the second half of the power despite being incapacitated.
Edit: It's Case 12629 if you're looking for the bug report, MigrantP.