BAN HIM!
RABBLE RABBLE RABBLE
MUTINY MUTINY MUTINY
This issue is that this is such a large quantum leap in logic that it needs a rational behind it. For a thought excercise, if the keyword "Drug" was inherently indestructible, wouldn't stating so in the text box be redundant? For as valuable as text space is, and for how crammed the Drug cards actually are, if it were as you say, there would have been no need at all for it to be in the text box.
SO, here's the deal. When Spite's character card refers to flipping over the Drug cards, it's talking about those face down cards which we know to be face down. That said, when they're face down, they don't do anything. Including have keywords or game text. So! You could totally Into the Stratosphere one, but it would be the next card played, so that's not really optimal. You could attempt to End of Days them or Cedistic Dissonant them, but cards go into the Trash face up, so we'd then see the text that indicates that if these cards would ever be put in the trash for any reason, put them into play instead, so that's even worse! They'd come back into play face up! Not helpful.
Anyway, I hope this helps understand how Spite: Agent of Gloom works.
This actually does not help me understand. Maybe it's the lack of sleep I've had this week, but I am having difficulty unambiguously parsing that statement.
Do you mean they do nothing, so much nothing that they have no keywords and no game text?
Or do you mean they do nothing, even though they do have keywords and game text?
Thanks for the clarification (does it ever surprise you what things we end up having long discussions about?).
The fact that they are indeed able to be Strata'd should have cleared just about every confusion discussed here (whether directly or indirectly).
Next topic!
What do you guys think we will see out of his flip side? It's not hard to see that EmoSpite will be flipping eventually. What will become of his drugs? Will he become a drug wrecked gloomy monstrosity?
@Jaymann, he means that they do nothing because they have no text/keywords.
Actually, please spell it out for me. I didn’t know that cards under Savage Mana were face down. We did not know how face down cards worked until Christopher said so.
@Christopher
So the intent is to put it back, and then it could get buried with Infrared or Visionary?
First, Ill appologize for that comming off as combative. I really like these discussions as you know, so that wasn't my intent 
Secondly, after you mentioned this, I might have just been putting cards under savage mana facedown since I originally bought it just out of a natural inclination to do so. Same with Omni-Cannon. Yeah, I know it does not explicitly tell you to do that, in which case your are technically correct. But all things considered at this point, I think it's appropriate to put them under savage mana face down, keeping it in line with all other similar effects of putting some cards under others. If it looses its text/keywords but remains in play, chances are pretty solid the card is supposed to be flipped over
But you don't have any "that kind of thing"…it's two mentions (one of them fairly speculative), which doesn't strike me as "heavy".
I put them facedown too! 
Akash'bhuta and Matriarch's flip mechanics are pretty similar, they just differ in which deck is being reshuffled. And all of The Dreamer, Citizen Dawn, and Grand Warlord Voss flip when their doods have all been pwned, though they have very different conditions for flipping back (never, only once, and every time doods-havingness is reestablished). I don't think it's too unreasonable for Gloomskinner to flip much the same way Baron Blade does.
I for one think it'd be absolutely hilarious if Gloomskinner's back is exactly the same as normal Gloomweaver's, given how you very rarely actually flip normal Gloomy.
Don't make me turn this car around. I will. I swear to sweat baby raptorbots I will.
Precognition is go!
I want the flip side of Skinwalker Gloomweaver to be Skincovered Gloomweaver, and to reveal that with skin it looks like... Paul.
We've got Chris and Adam on cards, why can this not be Paul's turn to shine?
Legacy is named after him.
Well aware, we just haven't got his picture on a card (Unless Legacy is a romanticised Paul).
What are you talking about? Haven't you met Paul? The guy is built like a brick s***house. 
Wait, Paul's real name is Legacy? or Parson's? Or maybe Paul Revere was also named after Paul.
I just want to say
What kind of miracle microscope do you people have that let you /read/ anything off that pic of the setup cards? Dear GOD that was small and blurry!
It's a kind of magic.
I thought there could only be one?